FGF23 Antibody

SKU: orb1410174

Description

Mouse monoclonal antibody to FGF23 (Fibroblast Growth Factor 23)

Research Area

Cancer Biology, Cardiovascular Research, Infectious Disease & Virology, Signal Transduction

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: FGF23/4171
• Immunogen: Recombinant fragment (around aa25-251) of human FGF23 protein (exact sequence is proprietary)
• Target: FGF23
• Source/Expression System: Bioreactor
• Molecular Weight: 12-32kDa
• Purification: Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

ADHR; FGF-23; FGFN; Fibroblast growth factor 23; HPDR2; HYPF; Phosphatonin; PHPTC; Tumor-derived hypophosphatemia-inducing factor

Analysis of Protein Array containing more than 19000 full-length human proteins using FGF23-Monospecific Mouse Monoclonal Antibody (FGF23/4171). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human kidney stained with FGF23 Mouse Monoclonal Antibody (FGF23/4171) at 2 ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.

IHC analysis of formalin-fixed, paraffin-embedded human kidney stained with FGF23/4171 2 ug/ml in PBS for 30 min RT. HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Quick Database Links

Gene Symbol

FGF23

UniProt

Q9GZV9