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ERK1/2 inhibitor 13

SKU: orb2945018

Description

ERK1/2 inhibitor 13 (Compound 21y) is an orally active dual ERK1/2 inhibitor with nanomolar IC50 values. It demonstrates potent anti-proliferative, pro-apoptotic, and anti-migratory effects in vitro in breast cancer cell lines and shows significant anti-tumor and anti-metastatic efficacy in a 4T1 mouse xenograft model.

Research Area

Cell Biology, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Images & Validation

Key Properties

MW727.54
FormulaC36H29BrF6N4O
TargetApoptosis,Autophagy,ERK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information