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STE-MEK1(13)

SKU: orb2276938

Description

STE-MEK1(13) is a cell-permeable small molecule inhibitor of ERK1/2, exhibiting IC50 values between 13 and 30 μM. It effectively blocks ERK1/2 phosphorylation and is utilized in vitro and in vivo to investigate MAPK/ERK signaling pathways in cancer and cellular proliferation research.

Research Area

Signal Transduction

Images & Validation

Key Properties

TargetERK
CAS Number566872-15-9
MW1757.32
FormulaC86H153N19O17S
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC(CCCCCCCCCCCCCCCCC)=O)CCSC)=O)CCC1)CCCCN)=O)CCCCN)=O)CCCCN)(=O)N2[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N)=O)CCC4)CC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCC3)[C@@H](C)O)=O)CCC2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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