Epratuzumab Antibody

SKU: orb1980638

Description

Epratuzumab (AMG 41) is a humanized anti-CD22 monoclonal antibody used in autoimmune disease research. It acts as a tumor imaging agent and induces CD22 phosphorylation, facilitating its study in both in vitro assays and in vivo experimental models.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	205923-57-5
MW	146.58 kDa
Purity	>95%
Target	Immunology/Inflammation related,Others

Bioactivity

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In Vitro	Epratuzumab binds to the CD22 extracellular domain with an affinity of K (D) = 0.7 nM. Epratuzumab binds to B cell lines or primary B cells from patients with NHL, resulting in rapid internalization of the CD22/ antibody complex. Read more...

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Anti-Human CD22 Recombinant Antibody, Antibody hLL 2, AMG41, AMG 41

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Gene Symbol

Immunology/Inflammation related,Others

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