EpCAM Antibody

SKU: orb2806656

Description

EpCAM Antibody

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: ELISA, FC, IHC, WB
• Reactivity: Human
• Application Notes:
  Immunohistochemistry was performed on human metastatic breast cancer tissue using this antibody (Schmidt et al, 2010; pmid:19633042). ELISA was performed on recombinant EpCAM protein using this antibody (Raum et al, 2000; pmid:11419181). Flow cytometry using this antibody was done on cells (Raum et al, 2000; pmid:11419181). Western blot was performed on 119 polypeptides of 13 amino acids shifted by two amino acids covering the entire extracellular domain of EpCAM. This antibody was used (Raum et al, 2000; pmid:11419181). Surface plasmon resonance was performed on the EpCAM protein using this antibody (Raum et al, 2000; pmid:11419181). This antibody was used for flow cytometery on KATO III cells (Naundorf et al, 2002; pmid:12115595). A cytotoxicity experiment was performed on PMBC using this antibody (Naundorf et al, 2002; pmid:12115595). Phase II trials were performed on prostate cancer patients (Marschner et al, 2010; pmid:20606402). Phase I trials were performed on prostate cancer patients (Oberneder et al, 2006; pmid:16930989).

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Key Properties

• Host: Human
• Clonality: Monoclonal
• Isotype: IgG
• Clone No.: MT201 (Adecatumumab; HD69)
• Immunogen: The original antibody was generated by panning against a naturally expressed human library.
• Target: EpCAM
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CD326; Ep-CAM; KS1/4 antigen; KSA; Epithelial cell adhesion molecule; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; 17-1A-antigen; EGP314; hEGP314; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; EGP-2; EGP40; KSA; CO17-1A; GA733-2

Quick Database Links

Gene Symbol

EpCAM

UniProt

P16422