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EP3 antagonist 4

SKU: orb1819027

Description

EP3 antagonist 4 is a potent and selective human EP3 receptor antagonist (Ki = 2 nM) with favorable pharmacokinetic properties, including low clearance and high oral bioavailability in rats. This compound is a valuable research tool for investigating the role of EP3 signaling in diabetes and related metabolic dysfunction in both in vitro and in vivo models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2408297-80-1
MW577.91
FormulaC22H20Cl3FN4O3S2
SMILESC(N1C\2=C(C=N1)CCC/C2=C(\CNC(NS(=O)(=O)C3=CC(C)=C(Cl)S3)=O)/F)C4=C(Cl)C=C(Cl)C=C4
TargetProstaglandin Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information