AH 6809

SKU: orb1308682

Description

AH 6809 is a prostaglandin receptor antagonist with selectivity for EP and DP subtypes, exhibiting Kis in the nanomolar range for human EP1, EP2, EP3-III, and DP receptors, as well as for the mouse EP2 receptor. This compound is a valuable research tool for investigating prostanoid signaling in both in vitro and in vivo models of inflammation, pain, and cardiovascular function.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 33458-93-4
• MW: 298.29
• Purity: 97.59% (May vary between batches)
• Formula: C₁₇H₁₄O₅
• SMILES: CC(C)Oc1ccc2c(c1)oc1ccc(cc1c2=O)C(O)=O
• Target: Prostaglandin Receptor
• Solubility: DMSO:25 mg/mL (83.81 mM);H2O:< 0.1 mg/mL (insoluble)

Bioactivity

• Target IC50:
  EP2:1150 nM (Ki)(human)|EP2:350 nM (Ki)(mouse)|DP:1415 nM (Ki)(human)|EP3:1597 nM (Ki)(human)|EP1:1217 nM (Ki)(human)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ProstaglandinReceptor, Prostaglandin Receptor, DP, AH6809, AH-6809, AH 6809, Inhibitor, EP3, EP1, EP2, inhibit

Compound Identifiers

PubChem CID

119461