Dehydrocorydaline

SKU: orb1301239

Description

Dehydrocorydaline (13-Methylpalmatine) is a bioactive small molecule with demonstrated anti-metastatic, antiplatelet, and anti-inflammatory properties in vitro. It modulates key pathways including MMPs, Bcl-2/Bax, and p38 MAPK, affecting cancer cell apoptosis, myoblast differentiation, and platelet aggregation, making it a valuable research tool in oncology, cardiovascular, and inflammation studies.

Research Area

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 30045-16-0
• MW: 366.43
• Purity: 99.84%
• Formula: C₂₂H₂₄NO₄
• SMILES: CC1=C2C=3C(=CC(OC)=C(OC)C3)CC[N+]2=CC=4C1=CC=C(OC)C4OC
• Target: Parasite,p38 MAPK,PARP,Bcl-2 Family,Caspase,Autophagy
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.65 mM);DMSO:66 mg/mL (180.12 mM)

Bioactivity

• Target IC50:
  Platelet:34.914 ug/mL

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Parasite, PARP, inhibit, Inhibitor, Dehydrocorydalin, Dehydrocorydaline, Autophagy, Bcl-2 Family, Bcl-2, Caspase, 13-Methylpalmatine, poly ADP ribose polymerase, p38 MAPK, p38MAPK

Compound Identifiers

PubChem CID

34781