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Dehydrocorydaline (hydroxyl)

SKU: orb3142020

Description

Dehydrocorydaline hydroxyl (13-Methylpalmatine) is an alkaloid that modulates the expression of Bax and Bcl-2 proteins, activates caspase-7 and caspase-8, and inactivates PARP. It enhances the activation of p38 MAPK and exhibits anti-inflammatory and anticancer properties. Additionally, it shows potent antimalarial activity with low cytotoxicity (cell viability > 90%) against the P. falciparum 3D7 strain (IC50 = 38 nM).

Research Area

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

TargetAutophagy,Parasite,PARP,Bcl-2 Family,p38 MAPK,Caspase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information