CXCR1 antibody

• Catalog Number: orb10487
• Category: Antibodies
• Description: CXCR1 antibody
• Target: CXCR1
• Clonality: Polyclonal
• Species/Host: Rabbit
• Isotype: IgG
• Conjugation: Unconjugated
• Form/Appearance: 10 mM PBS, 0.02% sodium azide
• Concentration: - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml
• Purity: Polyclonal antibodies are purified by peptide affinity chromatography
• Immunogen: KLH conjugated synthetic peptide derived from human CXCR1. Please contact us for the exact immunogen sequence. The peptide is available as orb12890.
• UniProt ID: P25024, P70612, Q810W6
• RRID: AB_10761323
• MW: 40 kDa
• Tested applications: ICC, IF, IHC-P, WB
• Dilution range: WB: 1:100-800, IHC-P: 1:100-600, IF/ICC: 1:100-600
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only
• Entrez: 3577
• NCBI: 000625

References

Dutta, Puja et al. Regulation of Staphylococcus aureus-induced CXCR1 expression via inhibition of receptor mobilization and receptor shedding during dual receptor (TNFR1 and IL-1R) neutralization Immunol Res, 67, 241-260 (2019)

PubMed: 31290001

Applications

WB

Reactivity

Mouse

Dutta, Puja et al. Neutralization of TNF-α and IL-1β Regulates CXCL8 Production through CXCL8/CXCR1 Axis in Macrophages during Staphylococcus aureus Infection Immunol. Invest., (2020)

PubMed: 32602757

Applications

WB

Reactivity

Mouse

Bishayi, Biswadev et al. Expression of CXCR1 (interleukin-8 receptor) in murine macrophages after staphylococcus aureus infection and its possible implication on intracellular survival correlating with cytokines and bacterial anti-oxidant enzymes Inflammation, 38, 812-827 (2015)

PubMed: 25129059

Applications

WB

Reactivity

Mouse

Nandi, Ajeya et al. Murine macrophage response from peritoneal cavity requires signals mediated by chemokine receptor CCR-2 during Staphylococcus aureus infection Immunol Res, 64, 213-232 (2016)

PubMed: 26616292

Applications

WB

Reactivity

Mouse

IF image of guinea pig skin tissue using CXCR1 antibody (2.5 ug/ml)

IHC-P image of rat lymph node tissue using anti-CXCR1 (2.5 ug/ml)

Western blot analysis of rat spleen (lane 1), mouse spinal cord (lane 2), rat skin (lane 3), rat lymph node (lane 4), human breast tumour (lane 5); 293t cells (lane 6) using anti-CXCR1 (1 ug/ml)

IF analysis of guinea pig skin tissue using anti-CXCR1 (2.5 ug/ml)

IHC-P image of guinea pig skin tissue using anti-CXCR1 (2.5 ug/ml)