IL8 Antibody Discontinued

SKU: orb229133

Description

Rabbit polyclonal antibody to interleukin 8 is also known as IL8/NAP1 form V and MDNCF whose expression can be detected by ER stress in a DDIT3/CHOP-dependent manner. It is found in the extracellular space. This protein has a 5-10-fold higher activity on neutrophil activation and IL-8(5-77) has increased activity on neutrophil activation along with IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation.

Research Area

Epigenetics, Immunology

Images & Validation

• Tested Applications: IHC-P, WB
• Dilution Range: WB: 1:500-2000, IHC-P: 1:50-200
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-310C antibody, anti-9E3 antibody, anti-AMCF1 antibody, anti-CEF-4 antibody, anti-chemokine, CXC motif, ligand 8 antibody, anti-CXC chemokine ligand 8 antibody, anti-CXC chemokine ligand 8 antibody, anti-CXCL 8 antibody, anti-Emoctakin antibody, anti-GCP 1 antibody, anti-GCP-1 antibody, anti-GCP1 antibody, anti-Granulocyte chemotactic protein 1 antibody, anti-IL 8 antibody, anti-IL8/NAP1 form I antibody, anti-Inteleukin 8 antibody, anti-Interleukin8 antibody, anti-K60 antibody, anti-LECT antibody, anti-LECT antibody, anti-LYNAP antibody, anti-MDNCF antibody, anti-Monocyte derived neutrophil activating peptide antibody, anti-NAF antibody, anti-NAP 1 antibody, anti-Neutrophil activating factor antibody, anti-Neutrophil activating factor antibody, anti-Neutrophil activating peptide 1 antibody, anti-SCYB8 antibody, anti-T-cell chemotactic factor antibody, anti-TSG1 antibody

Thanh-Tam Tran, Gyuseok Lee, Yun Hyun Huh, Ki-Ho Chung, Sun Young Lee, Ka Hyon Park, Seung Hee Kwon, Min-Suk Kook, Jang-Soo Chun, Jeong-Tae Koh, Je-Hwang Ryu Disruption of cholesterol homeostasis triggers periodontal inflammation and alveolar bone loss Exp Mol Med, (2023)

PubMed: 38036731

Applications

IHC

Reactivity

Human

Milorad Miljic 1, Sanja Vlaisavljevic Krstic 2, Mirjana Nacka-Aleksic 3, Aleksandra Jovanovic 4, Dragana Dekanski 5, Jelena Antic Stankovic 5, Dragana D Bozic 5, Milica Jovanovic Krivokuca 3, Zanka Bojic Trbojevic 3, Andrea Pirkovic 2 Biological activity of pumpkin pulp extracts: cytoprotection, anti-inflammatory effects, and photoprotection in human skin cells Cutan Ocul Toxicol, (2025)

PubMed: 41071954

He, Yong et al. Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model J Affect Disord, 271, 262-271 (2020)

PubMed: 32479325

Applications

WB

Reactivity

Mouse