Cullin 1 Rabbit mAb [KD Validated]

SKU: orb1950879

Description

Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.

Images & Validation

• Tested Applications: FC, ICC, IHC, IP, WB
• Dilution range: WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40 FC 1:30
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Recombinant
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Cullin 1
• Purification: Affinity-chromatography

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Disclaimer: For research use only

Alternative Names

CUL1; Cullin1;

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Cullin 1 expression in MCF-7 cell lysate.

Quick Database Links

UniProt

Q13616