COPS3 Rabbit mAb [KD Validated]

• Catalog Number: orb1727151
• Category: Antibodies
• Description: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.
• Species/Host: Rabbit
• Clonality: Recombinant
• Tested applications: FC, ICC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human COPS3
• Antibody Type: Recombinant Antibody
• Dilution range: WB:1:500~1:2000ICC/IF:1:50~1:200IP:1:50FC:1:50
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Conjugation: Unconjugated
• MW: 48 kDa
• UniProt ID: Q9UNS2
• Source: Recombinant Rabbit
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: COP9 subunit 3; cops3; CSN3; JAB 1 containing sign
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of COPS3 expression in HeLa cell lysate.