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Catalog Number | orb248164 |
---|---|
Category | Antibodies |
Description | CHCR2, or Corticotropin releasing hormone receptor 2, is a receptor for CRH (corticotropin-releasing hormone), a neurotransmitter secreted by the hypothalamus in response to stress. There are three major isoforms of CHCR2: alpha, beta and gamma, differing in their N-terminus amino acid sequence. Isoform beta and gamma are expressed in the brain, with gamma expression highest in the septum and hippocampus, while alpha is expressed in the peripheral tissues of the brain. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | A recombinant protein fragment from the N-terminal portion of human CRHR2 was used as the immunogen for this antibody (1). |
Dilution range | Western blot: 0.5-2ug/ml |
Purity | Protein A affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This CRHR2 antibody is available for research use only. |
Entrez | 1395 |
UniProt ID | Q13324 |
Storage | Aliquot the CRHR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
Buffer/Preservatives | 1X PBS, pH 7.4 |
Note | For research use only |
Application notes | Provided assay concentrations are suggestions only, CRHR2 antibody titration may be required for optimal results.1. This antibody will detect the alpha (411 AA), beta (438 AA) and gamma (397 AA) isoforms of CRHR2. |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of human samples using CRHR2 antibody (primary antibody dilution at: at 05 ug/ml)
ELISA, IHC, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
ELISA, IF, IHC-P, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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