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Corynoxine

SKU: orb1301332

Description

Corynoxine is a tetracyclic oxindole alkaloid derived from Uncaria macrophylla. It functions as an autophagy enhancer, facilitating the clearance of α-synuclein via Akt/mTOR pathway inhibition, making it a useful research tool for studying neurodegenerative mechanisms in cellular models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number6877-32-3
MW384.47
Purity96.83% (May vary between batches)
FormulaC22H28N2O4
SMILESCC[C@@H]1CN2CC[C@]3([C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC)C(=O)Nc1ccccc31
TargetAutophagy
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.2 mM);DMSO:55 mg/mL (143.05 mM);Ethanol:50 mg/mL (130.05 mM);H2O:Insoluble

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Corynoxine, Autophagy, alkaloid, inhibit, mTOR, macrophylla, Inhibitor, synuclein Akt, oxindole, Uncaria, tetracyclic

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Corynoxine (orb1301332)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 130.00
1 ml x 10 mM (in DMSO)
$ 140.00
10 mg
$ 170.00
25 mg
$ 260.00
50 mg
$ 360.00
100 mg
$ 510.00
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