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Corynoxine B

SKU: orb1679009

Description

Corynoxine B is a natural autophagy inducer derived from Uncaria rhynchophylla that promotes Beclin-1/VPS34 complex activity via HMGB1/2 interaction. It is used in research on neurodegenerative diseases, such as Alzheimer's, and has been studied in both cellular and animal models for its neuroprotective potential.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number17391-18-3
MW384.47
Purity99.72%
FormulaC22H28N2O4
SMILESO=C1[C@@]2([C@]3(N(CC2)C[C@@H](CC)[C@@H](\C(\C(OC)=O)=C/OC)C3)[H])C=4C(N1)=CC=CC4
TargetAutophagy
SolubilityDMSO:80 mg/mL (208.08 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.58 mM)

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

Corynoxine B, Autophagy, Beclin1, α-synuclein
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Corynoxine B (orb1679009)

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