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Catalog Number | orb1729810 |
---|---|
Category | Antibodies |
Description | Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | FC, IHC, IP, WB |
Reactivity | Human, Monkey, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | A synthetic peptide of mouse CNOT7 |
Dilution range | IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100; RCM: 1/50-1/100 |
Conjugation | Unconjugated |
MW | Calculated MW: 33 kDa; Observed MW: 33 kDa |
Entrez | 18983 |
UniProt ID | Q60809 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | CCR4-associated factor 1; CAF-1 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
IF, IHC-P, WB | |
Bovine, Gallus, Mouse, Xenopus, Zebrafish | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |
IF, IHC-P, WB | |
Mouse, Other, Zebrafish | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |
FC, IHC-P, IP, WB | |
Human, Monkey, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
IH, WB | |
Human, Mouse, Primate, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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