Clopidogrel thiolactone

SKU: orb1226911

Description

A thienopyridine-class antiplatelet agent that works by irreversibly inhibiting P2Y12 receptor on platelets; used to reduce the risk of heart disease and stroke in those at high risk.Thrombosis Approved.

Key Properties

• CAS Number: 1147350-75-1
• MW: 337.8211
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₆ClNO₃S
• SMILES: O=C(OC)[C@H](C1=CC=CC=C1Cl)N2CCC3C(C2)=CC(S3)=O
• Target: P2Y Receptor
• Solubility: 10 mM in DMSO

Bioactivity

• In Vivo:
  Clopidogrel thiolactone (8 μm/kg; i. v. ; Sprague-Dawley male rats) has good biological availability and pharmacokinetic parameters. Animal model: Sprague-Dawley male rats. Dosage: 8 μm/kg; orally clopidogrel (24 μm/kg). Administration: Intravenous injection; collected blood at 0 h (before dosing) and 0.083, 0.167, 0.5, 1, 2, 4, 6, 8, 24 h postdose.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2-Oxo-clopidogrel | Clopidogrel thiolactone | 2-Oxoclopidogrel

Quick Database Links

Gene Symbol

P2Y Receptor