2-oxo Clopidogrel

SKU: orb1693930

Description

2-oxo Clopidogrel ((±)-SR-121683) is a key thiolactone metabolite generated by CYP3A-mediated hepatic oxidation of the prodrug Clopidogrel. This intermediate is crucial for research into the metabolic activation pathway and can be hydrolyzed to form the active metabolite (CAM) in vitro, supporting pharmacological and pharmacokinetic studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 109904-27-0
• MW: 337.82
• Formula: C₁₆H₁₆ClNO₃S
• SMILES: O=C1SC2C(=C1)CN(CC2)C(C(=O)OC)C=3C=CC=CC3Cl
• Target: Drug Metabolite,Others
• Solubility: DMF:PBS (pH 7.2) (1:20):< 1 mg/mL, insoluble;Ethanol:5 mg/mL (14.8 mM);DMSO:200 mg/mL (592.03 mM);DMF:10 mg/mL (29.6 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2oxo Clopidogrel, 2-oxo Clopidogrel, 2 oxo Clopidogrel, (±)-2-Oxo clopidogrel, (±)-SR-121683

Compound Identifiers

PubChem CID

13748464