CHGA (C) Antibody, Rabbit Polyclonal

SKU: orb66936

Description

Rabbit polyclonal to CHGA.Chromogranin A or parathyroid secretory protein 1 (CHGA) is a member of the granin family ofneuroendocrine secretory proteins. CHGA is located in secretory vesicles of neurons and endocrinecells, and is the precursor to several functional peptides including vasostatin, pancreastatin, catestatinand parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell(autocrine) or nearby cells (paracrine). CHGA is elevated in pheochromocytomas and diabetes.CHGA is also used as an indicator for pancreas and prostate cancer and in carcinoid syndrome.

Research Area

Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human CHGA
• Molecular Weight: 51
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-CHGA antibody,anti-ChromograninA antibody,anti-CgA antibody,anti-Pituitary secretory protein I antibody,anti-SPI antibody

Western blot analysis of total cell extracts from mouse pancreas using CHGA antibody

Quick Database Links

UniProt

P10645