CD79b Antibody

• Catalog Number: orb1824990
• Category: Antibodies
• Description: CD79 (also designated Ig Alpha/Ig beta) is a heterodimer composed of Alpha chains, designated CD79A or MB-1, and beta chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: CD79b/4960
• Tested applications: ELISA, IHC-P
• Reactivity: Human
• Isotype: Mouse IgG1, kappa
• Immunogen: A recombinant fragment of human CD79b protein was used as the immunogen for the CD79b antibody.
• Dilution range: ELISA: 2-4mg/ml for coating (order BSA-free format),Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This CD79b antibody is available for research use only.
• UniProt ID: P40259
• Storage: Aliquot the CD79b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.