CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody

• Catalog Number: orb1410021
• Category: Antibodies
• Description: Mouse monoclonal antibody to CD35
• Target: CR1
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: IgG2b
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Purification: Protein A
• Immunogen: Recombinant fragment (within aa650-850) of human CD35 (exact sequence is proprietary)
• UniProt ID: P17927
• MW: 224kDa
• Tested applications: IHC
• Clone Number: CR1/6378
• Expression System: Bioreactor
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: C3 binding protein, C3b/C4b receptor, C3BR, C4BR,
• Research Area: Epigenetics & Chromatin, Immunology & Inflammation
• Note: For research use only

Analysis of Protein Array containing >19000 full-length human proteins using Monospecific to CD35 Mouse Monoclonal Antibody (CR1/6378). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human spleen stained with CD35 Mouse Monoclonal Antibody (CR1/6378) at 2 ug/ml. HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Formalin-fixed, paraffin-embedded human tonsil stained with CD35 Mouse Monoclonal Antibody (CR1/6378) at 2 ug/ml. HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

SDS-PAGE Analysis of Purified CD35 Mouse Monoclonal Antibody (CR1/6378). Confirmation of Purity and Integrity of Antibody.