CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody

SKU: orb1410506

Description

Mouse monoclonal antibody to CD35

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: CR1/6383
• Immunogen: Recombinant fragment (within aa650-850) of human CD35 (exact sequence is proprietary)
• Target: CR1
• Source/Expression System: HEK293 cells
• Molecular Weight: 224kDa

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen

Analysis of Protein Array containing >19000 full-length human proteins using Monospecific to CD35 Mouse Monoclonal Antibody (CR1/6383). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human tonsil stained with CD35 Mouse Monoclonal Antibody (CR1/6383) at 2 ug/ml.

Formalin-fixed, paraffin-embedded human tonsil stained with CD35 Mouse Monoclonal Antibody (CR1/6383) at 2 ug/ml.

SDS-PAGE Analysis of Purified CD35 Mouse Monoclonal Antibody (CR1/6383). Confirmation of Purity and Integrity of Antibody.

Quick Database Links

Gene Symbol

CR1

UniProt

P17927