CCR7 (N) Antibody, Rabbit Polyclonal

SKU: orb67198

Description

Rabbit polyclonal to CCR7.C-C chemokine receptor type 7 (CCR7) is a receptor for the MIP-3-beta chemokine and belongs tothe G-protein coupled receptor 1 family. CCR7 was identified as a gene induced by the Epstein-Barrvirus (EBV) and is a probable mediator of EBV effects on B-lymphocytes as well as of normallymphocyte functions. CCR7 is expressed in various lymphoid tissues and activates B and Tlymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as wellas to stimulate dendritic cell maturation. CCR7 is strongly up-regulated in B-cells infected withEpstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

Images & Validation

• Tested Applications: WB
• Dilution range: WB:1:1000-1:3000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human CCR7
• Molecular Weight: 43
• Purity: Affinity purification

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Disclaimer: For research use only

Western blot analysis of total cell extracts from mouse spleen(Lane1) and human K562(Lane2) using CCR7 antibody

Quick Database Links

UniProt

P32248