CCR5 (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb67200
• Category: Antibodies
• Description: Rabbit polyclonal to CCR5.C-C chemokine receptor type 5 (CCR5) is a multi-pass membrane protein that belongs to the Gproteincoupled receptor 1 family. It is a receptor for a number of inflammatory CC-chemokinesincluding MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasingthe intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferationor differentiation. CCR5 acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Genetic variation in CCR5 is associated with susceptibility to diabetes mellitus insulin-dependent type22 (IDDM22).
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: 0.01% NaN3
• Purity: Affinity purification
• Immunogen: C-terminal region of human CCR5
• UniProt ID: P51681
• MW: 41
• Tested applications: WB
• Dilution range: WB:1:1000-1:3000
• Storage: -20°C
• Alternative names: anti-CCR5 antibody,anti-CC chemokine receptor type
• Note: For research use only

Western blot analysis of total cell extracts from mouse brain using CCR5 antibody