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Catalog Number | orb1730545 |
---|---|
Category | Antibodies |
Description | Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | ICC, IHC, WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | A synthesized peptide derived from human Caveolin-1 |
Dilution range | WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 20 kDa; Observed MW: 25 kDa |
Entrez | 857 |
UniProt ID | Q03135 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Alternative names | CAV1; CAV; Caveolin-1 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
IF, IHC, IHC-Fr, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
IHC-P, WB | |
Human, Mouse, Porcine, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
FC, IF, IHC, IHC-Fr, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
ELISA, FC, IF, IHC, WB | |
Canine, Human, Mouse, Porcine, Rat | |
Goat | |
Polyclonal | |
Unconjugated |
ELISA, FC, IF, WB | |
Canine, Mouse, Porcine, Rat | |
Human | |
Goat | |
Polyclonal | |
Unconjugated |
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