Canakinumab

• Catalog Number: orb1983526
• Category: Antibodies
• Description: Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.
• Clonality: Recombinant
• CAS Number: 914613-48-2
• Antibody Type: Recombinant Antibody
• Concentration: 2.74 mg/mL
• Purity: 98.3% (SEC-HPLC)
• Conjugation: Unconjugated
• MW: 145.18 kDa
• Target: Canakinumab
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.