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A-23187

SKU: orb1309881

Description

Calcimycin

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number52665-69-7
MW523.62
Purity>98%
FormulaC29H37N3O6
SMILESCNc1ccc2oc(C[C@H]3OC4(CC[C@H]3C)O[C@H]([C@H](C)C(=O)c3ccc[nH]3)[C@H](C)C[C@H]4C)nc2c1C(O)=O
TargetIonophore
SolubilitySoluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).

Bioactivity

In Vivo
Calcimycin (2.5 or 7.5 nM; intrapleurally) induces protein leakage .
In Vitro
Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner .

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Calcimycin

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Key Properties

No computed properties available.

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Protocol Information

A-23187 (orb1309881)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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5 mg
$ 200.00
25 mg
$ 370.00
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