Calcimycin

SKU: orb1309881

Description

Calcimycin

Research Area

Cell Biology, Infectious Disease & Virology

Key Properties

• CAS Number: 52665-69-7
• MW: 523.62
• Purity: 98.00%
• Formula: C₂₉H₃₇N₃O₆
• SMILES: CNc1ccc2oc(C[C@H]3OC4(CC[C@H]3C)O[C@H]([C@H](C)C(=O)c3ccc[nH]3)[C@H](C)C[C@H]4C)nc2c1C(O)=O
• Target: Autophagy,OXPHOS,Antifungal,Antibiotic,Antibacterial,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.82 mM);DMSO:47 mg/mL (89.76 mM)

Bioactivity

• In Vivo:
  Calcimycin (2.5 or 7.5 nM; intrapleurally) induces protein leakage.
• In Vitro:
  Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner .

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

divalent, cation, A23187, A-23187, A 23187, Autophagy, Apoptosis, Antifungal, Antibiotic A 23187, Antibiotic A23187, Antibiotic A-23187, Antibiotic, Calcimycin, Bacterial, bacteria, mycobacterial, ionophore, Inhibitor, inhibit, Gram-positive, Fungal, phosphorylation

Compound Identifiers

PubChem CID

11555468