Calcimycin hemimagnesium

SKU: orb1981786

Description

Calcimycin hemimagnesium (A-23187) is a divalent cation ionophore that elevates intracellular calcium, inducing Ca2+-dependent cell death and apoptosis. It is widely used in research to study mitochondrial dysfunction, uncouple oxidative phosphorylation, and investigate mechanisms of cytotoxicity in both cellular and microbiological assays.

Research Area

Cell Biology, Infectious Disease & Virology

Key Properties

• CAS Number: 72124-77-7
• MW: 1069.53
• Formula: C₅₈H₇₂MgN₆O₁₂
• SMILES: O=C1[O-][Mg+2]234([N]=5C=6C(C(=O)[O-]2)=C(NC)C=CC6OC5CC7OC8(OC(C(C)C(=O3)C9=CC=CN9)C(C)CC8C)CCC7C)[N]=%10C=%11C1=C(NC)C=CC%11OC%10CC%12OC%13(OC(C(C)C(=O4)C%14=CC=CN%14)C(C)CC%13C)CCC%12C
• Target: Apoptosis,OXPHOS,Antibacterial,Autophagy,Antifungal,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,OXPHOS,Antibacterial,Autophagy,Antifungal,Others