Calcimycin hemimagnesium

• Catalog Number: orb1981786
• Category: Small Molecules
• Description: Calcimycin (A-23187) hemimagnesium, an antibiotic and divalent cation ionophore (such as calcium and magnesium), serves various biological roles. It triggers Ca2+-dependent cell death by elevating intracellular calcium levels and suppresses the growth of Gram-positive bacteria and certain fungi. Additionally, this compound hinders ATPase activity and uncouples oxidative phosphorylation (OXPHOS) in mammalian cells, ultimately leading to apoptosis [1] [2] [3] [4].
• CAS Number: 72124-77-7
• Purity: 98.00%
• MW: 1069.53
• SMILES: O=C1[O-][Mg+2]234([N]=5C=6C(C(=O)[O-]2)=C(NC)C=CC6OC5CC7OC8(OC(C(C)C(=O3)C9=CC=CN9)C(C)CC8C)CCC7C)[N]=%10C=%11C1=C(NC)C=CC%11OC%10CC%12OC%13(OC(C(C)C(=O4)C%14=CC=CN%14)C(C)CC%13C)CCC%12C
• Formula: C₅₈H₇₂MgN₆O₁₂
• Biological Activity: Calcimycin (A-23187) hemimagnesium, an antibiotic and divalent cation ionophore (such as calcium and magnesium), serves various biological roles. It triggers Ca2+-dependent cell death by elevating intracellular calcium levels and suppresses the growth of Gram-positive bacteria and certain fungi. Additionally, this compound hinders ATPase activity and uncouples oxidative phosphorylation (OXPHOS) in mammalian cells, ultimately leading to apoptosis [1] [2] [3] [4].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.