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Calcimycin hemimagnesium

SKU: orb1981786

Description

Calcimycin hemimagnesium (A-23187) is a divalent cation ionophore that elevates intracellular calcium, inducing Ca2+-dependent cell death and apoptosis. It is widely used in research to study mitochondrial dysfunction, uncouple oxidative phosphorylation, and investigate mechanisms of cytotoxicity in both cellular and microbiological assays.

Research Area

Cell Biology, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number72124-77-7
MW1069.53
FormulaC58H72MgN6O12
SMILESO=C1[O-][Mg+2]234([N]=5C=6C(C(=O)[O-]2)=C(NC)C=CC6OC5CC7OC8(OC(C(C)C(=O3)C9=CC=CN9)C(C)CC8C)CCC7C)[N]=%10C=%11C1=C(NC)C=CC%11OC%10CC%12OC%13(OC(C(C)C(=O4)C%14=CC=CN%14)C(C)CC%13C)CCC%12C
TargetApoptosis,Autophagy,OXPHOS,Antibacterial,Others,Antifungal

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Calcimycin hemimagnesium (orb1981786)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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