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Cabozantinib

Cabozantinib

Catalog Number: orb1223863

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Catalog Numberorb1223863
CategorySmall Molecules
DescriptionCabozantinib (XL184, BMS-907351) is a potent multi-kinase inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50 of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
TargetAXL|c-Met|Kit|VEGFR2/KDR|VEGFR3/FLT4|VEGFR2|MET|MET(Y1248H)|RET|FLT3
Purity> 98% (HPLC)
MW501.5
CAS Number849217-68-1
FormulaC28H24FN3O5
StorageStorage temperature: -20°C. Stability: ≥ 2 years
NoteFor research use only
  • Cabozantinib [orb1305297]

    99.88%

    [849217-68-1]

    501.51

    C28H24FN3O5

    200 mg, 100 mg, 50 mg, 10 mg, 5 mg, 500 mg, 1 ml x 10 mM (in DMSO)
  • Cabozantinib (S-malate) [orb1226924]

    > 98% (HPLC)

    1140909-48-3

    635.6

    C32H30FN3O10

    200 mg, 5 mg, 10 mg, 50 mg, 100 mg, 1 g, 500 mg
  • Cabozantinib hydrochloride [orb1302037]

    99.97%

    1817759-42-4

    537.96

    C28H25ClFN3O5

    2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg, 10 mg, 1 mg, 500 mg
  • Cabozantinib S-malate [orb1307421]

    98.87%

    [1140909-48-3]

    635.59

    C32H30FN3O10

    200 mg, 100 mg, 50 mg, 10 mg, 5 mg, 500 mg, 1 ml x 10 mM (in DMSO)