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Cabozantinib
Catalog Number: orb1305297
| Catalog Number | orb1305297 |
|---|---|
| Category | Small Molecules |
| Description | Cabozantinib |
| Purity | 99.88% |
| MW | 501.51 |
| Biological Activity | Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity. |
| CAS Number | [849217-68-1] |
| Formula | C28H24FN3O5 |
| SMILES | C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4(C(NC5=CC=C(F)C=C5)=O)CC4 |
| Storage | -20°C |
| Note | For research use only |
Cabozantinib hydrochloride [orb1302037]
99.97%
1817759-42-4
537.96
C28H25ClFN3O5
2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg, 10 mg, 1 mg, 500 mgCabozantinib S-malate [orb1307421]
98.87%
[1140909-48-3]
635.59
C32H30FN3O10
200 mg, 100 mg, 50 mg, 10 mg, 5 mg, 500 mg, 1 ml x 10 mM (in DMSO)
