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Catalog Number | orb1305297 |
---|---|
Category | Small Molecules |
Description | Cabozantinib |
Purity | 99.88% |
MW | 501.51 |
Biological Activity | Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity. |
CAS Number | [849217-68-1] |
Formula | C28H24FN3O5 |
SMILES | C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4(C(NC5=CC=C(F)C=C5)=O)CC4 |
Storage | -20°C |
Note | For research use only |
> 98% (HPLC) | |
849217-68-1 | |
501.5 | |
C28H24FN3O5 |
> 98% (HPLC) | |
1140909-48-3 | |
635.6 | |
C32H30FN3O10 |
99.97% | |
1817759-42-4 | |
537.96 | |
C28H25ClFN3O5 |
98.87% | |
[1140909-48-3] | |
635.59 | |
C32H30FN3O10 |