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BRAF inhibitor

SKU: orb1309908

Description

This small molecule BRAF inhibitor selectively targets the B-Raf kinase. It is a valuable research tool for studying oncogenic signaling in vitro and has been used in preclinical in vivo models of melanoma and other cancers driven by BRAF mutations.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number918505-61-0
MW456.47
Purity97.95% (May vary between batches)
FormulaC22H18F2N4O3S
SMILESCC(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2cccnc2)c1F
TargetRaf
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.38 mM);DMSO:75 mg/mL (164.3 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

B-Raf, BRAF inhibitor, inhibit, Inhibitor, Raf kinases, Raf

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

BRAF inhibitor (orb1309908)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 140.00
1 ml x 10 mM (in DMSO)
$ 150.00
10 mg
$ 190.00
25 mg
$ 310.00
50 mg
$ 460.00
100 mg
$ 630.00
200 mg
$ 900.00
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