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Catalog Number | orb1305565 |
---|---|
Category | Small Molecules |
Description | Vemurafenib |
CAS Number | 918504-65-1 |
Purity | 99.65% |
MW | 489.92 |
SMILES | C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CCC)(=O)=O)=CC=C4F |
Formula | C23H18ClF2N3O3S |
Biological Activity | Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[918504-65-1] | |
489.92 | |
C23H18ClF2N3O3S |
918504-65-1 |
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