Bimekizumab Antibody

SKU: orb1980645

Description

Bimekizumab is a humanized monoclonal antibody that simultaneously neutralizes IL-17A and IL-17F. It is a valuable research tool for studying psoriatic and arthritic disease mechanisms, supporting both in vitro assays of cytokine blockade and in vivo models of inflammation and bone biology.

Research Area

Immunology & Inflammation

Images & Validation

−

Key Properties

−

CAS Number	1418205-77-2
MW	147.24 kDa
Purity	100.00%
Target	IL Receptor,Interleukin

Bioactivity

−

In Vitro	Methods: Bimekizumab (10 μg/mL, 1 hour) was used to treat human periosteum-derived cells (hPDCs), and the expression of osteogenesis-related genes was analyzed by real-time quantitative PCR. Results: Bimekizumab effectively suppressed the expression of osteogenic genes through dual neutralization of IL-17A and IL-17F. Read more...

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

THPTA

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

IL Receptor,Interleukin

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols