Bimekizumab Human Monoclonal Antibody

SKU: orb2978529

Description

Research Grade Bimekizumabis a humanized monoclonal antibody detecting CTLA-8 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights Multi-Application: Validated across multiple applications.

Images & Validation

• Tested Applications: ELISA, FA, FACS, In vivo
• Reactivity: Human

Key Properties

• Antibody Type: Biosimilar Antibody
• Host: Human Humanized
• Clonality: Monoclonal
• Isotype: IgG1-kappa
• Source/Expression System: Mammalian Cells
• Purity: >95% as determined by SDS-PAGE.
• Purification: Protein A/G purified from cell culture supernatant.
• Endotoxin: Please contact with the lab for this information.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M PBS, pH 7.4.
• Concentration: 6.17 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A, IL17F, Interleukin-17F, IL-17F, Cytokine ML-1

Detects Human IL17A in indirect ELISAs.

Flow-cytometry using anti-human IL17A&IL17F antibody. Jurkat cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human IL17A&IL17F monoclonal antibody (Catalog orb2978529, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC and cells analysed on a NovoCyte Flow Cytometer.

SDS-PAGE for Research Grade Bimekizumab.

Western blot analysis was performed using anti-IL17A monoclonal antibody at 1 µg/mL on various samples. Lane 1: recombinant human IL17A (Catalog No: orb2967812), 50 ng, Lane 2: recombinant human IL17A (Catalog No: orb2967812), 30 ng, Lane 3: recombinant human IL17A (Catalog No: orb2967812), 20 ng, Lane 4: recombinant human IL17A (Catalog No: orb2967812), 10 ng.

Quick Database Links

UniProt

Q16552, Q96PD4