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BI-2852

SKU: orb1218330

Description

BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 is leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.

Images & Validation

Key Properties

CAS Number2375482-51-0
MW516.59
Purity>98% (HPLC)
FormulaC31H28N6O2
SMILESCn1cnc(Cn(cc2)c3c2ccc(CNCc2c([C@H](c4c5ccc(O)c4)NC5=O)c(cccc4)c4[nH]2)c3)c1
TargetRas
SolubilityDMSO:55 mg/mL (106.47 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Available Sizes

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500 mg
200 mg
5 mg
$ 460.00
10 mg
$ 680.00
25 mg
$ 1,110.00
50 mg
$ 1,520.00
100 mg
$ 2,090.00