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BCI

SKU: orb1309939

Description

BCI (E-BCI) is a cell-permeable, allosteric inhibitor of select DUSP proteins, notably DUSP6 and DUSP1, with cellular EC50 values of 13.3 and 8.0 μM, respectively, while sparing DUSP5. It is a valuable research tool for investigating ERK signaling pathways in cancer research and has been utilized in both cellular and in vivo studies to probe phosphatase function.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1245792-51-1
MW317.42
Purity>99.99% (May vary between batches)
FormulaC22H23NO
SMILESO=C1\C(=C\c2ccccc2)C(NC2CCCCC2)c2ccccc12
TargetPhosphatase
SolubilityDMSO:50 mg/mL (157.52 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (10.4 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BCI, (E)-BCI, phosphatase

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 130.00
5 mg
$ 160.00
10 mg
$ 240.00
25 mg
$ 360.00
50 mg
$ 520.00
100 mg
$ 710.00
DispatchUsually dispatched within 5-10 working days
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