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Aurora B inhibitor 1

SKU: orb1709148

Description

Aurora B inhibitor 1 is a potent and selective small molecule targeting the Aurora B kinase (Ki <0.010 µM). It is a valuable research tool for investigating mitotic regulation and has demonstrated utility in both in vitro cellular assays and in vivo xenograft models for cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number937276-52-3
MW529.97
Purity98.37% (May vary between batches)
FormulaC25H26ClF2N7O2
SMILESFC1(CN(C1)C2=NC(O[C@@H]3CN(C(=O)C4=C(F)C=CC(Cl)=C4)CC3)=NC(NC5=NNC(C)=C5)=C2)C6CC6
TargetAurora Kinase

Bioactivity

Target IC50
Aurora B:0.01 μM (Ki)
In Vitro
Aurora B inhibitor 1 inhibits JAK2 and JAK3 with Kis less than 0.10 μM and 0.25 μM, respectively.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Aurora Kinase, Aurora B inhibitor 1, AuroraKinase, Aurora B

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 740.00
5 mg
$ 1,840.00
DispatchUsually dispatched within 5-10 working days
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