Aurora B inhibitor 1

SKU: orb1709148

Description

Aurora B inhibitor 1 is a potent and selective small molecule targeting the Aurora B kinase (Ki <0.010 µM). It is a valuable research tool for investigating mitotic regulation and has demonstrated utility in both in vitro cellular assays and in vivo xenograft models for cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin

Images & Validation

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Key Properties

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CAS Number	937276-52-3
MW	529.97
Purity	98.37% (May vary between batches)
Formula	C₂₅H₂₆ClF₂N₇O₂
SMILES	FC1(CN(C1)C2=NC(O[C@@H]3CN(C(=O)C4=C(F)C=CC(Cl)=C4)CC3)=NC(NC5=NNC(C)=C5)=C2)C6CC6
Target	Aurora Kinase

Bioactivity

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Target IC50	Aurora B:0.01 μM (Ki)
In Vitro	Aurora B inhibitor 1 inhibits JAK2 and JAK3 with Kis less than 0.10 μM and 0.25 μM, respectively.

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Aurora Kinase, Aurora B inhibitor 1, AuroraKinase, Aurora B

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Compound Identifiers

PubChem CID

16731225 ↗

Key Properties

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No computed properties available.

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