Antifungal agent 68

• Catalog Number: orb1944227
• Category: Small Molecules
• Description: Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol biosynthesis, likely via interaction with lanosterol 14α-demethylase (CYP51). The imidazole ring of antifungal agent 68 is proposed to interact with the heme group of CYP51 [1].
• CAS Number: 2925307-53-3
• Purity: 98.00%
• MW: 414.93
• SMILES: O(CC(CN1C=CN=C1)OCC2=CC=C(Cl)C=C2)C3=C(OC)C=C(CCC)C=C3
• Formula: C₂₃H₂₇ClN₂O₃
• Biological Activity: Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol biosynthesis, likely via interaction with lanosterol 14α-demethylase (CYP51). It is proposed that the imidazole ring of antifungal agent 68 interacts with the heme group of CYP51 [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.