(Rac)-Amorolfine hydrochloride

SKU: orb1685354

Description

Amorolfine HCl is a morpholine-derived antifungal agent that selectively inhibits both Δ14-reductase and Δ7-Δ8 isomerase, key enzymes in ergosterol biosynthesis. This dual action depletes ergosterol and leads to ignosterol accumulation, disrupting fungal membrane integrity. It is widely used in research for studying antifungal mechanisms and efficacy in both in vitro and ex vivo models of dermatophyte and yeast infections.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 106614-68-0
• MW: 353.97
• Formula: C₂₁H₃₆ClNO
• SMILES: Cl.O1C(C)CN(CC1C)CC(C)CC2=CC=C(C=C2)C(C)(C)CC
• Target: Antibiotic,Antifungal

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

21989528