Anti-TNF alpha [D2E7 (Adalimumab)]

SKU: orb396142

Description

Mouse monoclonal antibody to TNF alpha.

Research Area

Immunology & Inflammation, Musculoskeletal & Connective Tissue Research

Images & Validation

• Tested Applications: Blocking, ELISA, IF, IHC
• Reactivity: Human

Key Properties

• Host: Human
• Clonality: Monoclonal
• Isotype: Human IgG
• Clone No.: D2E7 (Adalimumab)
• Immunogen: This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).
• Target: TNF alpha
• Purity: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tumor necrosis factor alpha

Quick Database Links

Gene Symbol

TNF alpha

UniProt

P01375

Jespers, L. S. et al. Guiding the selection of human antibodies from phage display repertoires to a single epitope of an antigen Biotechnology (N Y), 12, 899-903 (1994)

PubMed: 7521646