Anti-TNF alpha [D2E7 (Adalimumab)]

• Catalog Number: orb396138
• Category: Antibodies
• Description: Mouse monoclonal antibody to TNF alpha.
• Species/Host: Human
• Clonality: Monoclonal
• Clone Number: D2E7 (Adalimumab)
• Tested applications: Blocking, ELISA, IF, IHC
• Reactivity: Human
• Isotype: IgG1
• Immunogen: This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: TNF alpha
• UniProt ID: P01375
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Tumor necrosis factor alpha
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

Jespers, L. S. et al. Guiding the selection of human antibodies from phage display repertoires to a single epitope of an antigen Biotechnology (N Y), 12, 899-903 (1994)

PubMed: 7521646