Anti-OSMR Reference Antibody (vixarelimab)

• Catalog Number: orb1805635
• Category: Antibodies
• Description: Anti-OSMR Reference Antibody is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa.
• Clonality: Monoclonal
• Tested applications: ELISA, FA, FACS, Kinetics
• Reactivity: Human
• Isotype: IgG
• Purity: > 95%
• Conjugation: Unconjugated
• MW: 145.5 kDa
• Target: OSMR
• Endotoxins: < 1 EU/mg
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 100 mM Pro-Ac 20 mM Arg pH 5.0
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Anti-OSMR Reference Antibody (vixarelimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-OSMR Reference Antibody (vixarelimab)is more than 96.9% ;determined by SEC-HPLC.

Immobilized human OSMR His at 2 μg/mL can bind Anti-OSMR Reference Antibody (vixarelimab);EC50=0.0024μg/mL.

Human OSMR HEK293 cells were stained with Anti-OSMR Reference Antibody (vixarelimab) and negative control protein respectively; washed and then followed by PE and analyzed with FACS; EC261=0.0359 μg/mL.

Anti-OSMR Reference Antibody (vixarelimab) P-STAT3 Assay was evaluated using NHDF. The IC50 was approximately 0.3493 nM.

Anti-OSMR Reference Antibody (vixarelimab);MCP-1 secretion was evaluated using NHDF. The IC50 was approximately 0.0812 nM.