NLRP3 Rabbit Polyclonal Antibody

SKU: orb665921

Description

The NLRP3 Antibody is suitable for IF, IHC, WB. It is a Polyclonal, Unconjugated antibody which raised against Recombinant protein of human NLRP3. The exact sequence is proprietary. Purification: The antibody was purified by immunogen affinity chromatography.

Research Area

Cell Biology

Images & Validation

• Tested Applications: IF, IHC, WB
• Dilution Range: WB: 1-500-1000
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human NLRP3. The exact sequence is proprietary.
• Target: NLRP3
• Purification: The antibody was purified by immunogen affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

C1orf7; CIAS1; NALP3; PYPAF1; NACHT, LRR and PYD domains-containing protein 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1

Quick Database Links

Gene Symbol

NLRP3

UniProt

Q96P20, Q8R4B8

NCBI Gene ID

216799, 114548

Kimoto, Saki et al. Nacre extract derived from Pinctada fucata mitigates skeletal muscle aging by suppressing senescence-associated inflammation and preserving contractile features in naturally aged mice and C2C12 myotubes Asian Pacific Journal of Tropical Biomedicine, (2026)

PubMed:

Applications

IF

Reactivity

Mouse

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1 Molecular Medicine Reports, 17, 3212 (2017)

PubMed: 29257276

Applications

WB

Reactivity

Rat

Man Luo, Lijuan Hu, Dandan Li, Yanying Wang, Yuting He, Lei Zhu, Weiying Ren MD-2 regulates LPS-induced NLRP3 inflammasome activation and IL-1beta secretion by a MyD88/NF-κB-dependent pathway in alveolar macrophages cell line Mol Immunol ., 90, (2017)

PubMed: 28654770

Applications

WB

Reactivity

Rat

Ning Ding, Jing Jiang, Menghan Lu, Jiatong Hu, Yiyuan Xu, Xiaoxiao Liu, Zhigang Li Manual Acupuncture Suppresses the Expression of Proinflammatory Proteins Associated with the NLRP3 Inflammasome in the Hippocampus of SAMP8 Mice Evidence-based Complementary and Alternative Medicine, 2017, 8 (2017)

PubMed: 28904553

Applications

IHC, WB

Reactivity

Mouse

Momoko Kawaminami et al. Nacre extract attenuates age-related functional and tissue alterations under post-onset intervention conditions in two murine aging models Biogerontology, 27, 114 (2026) (2026)

PubMed: 42289617

Applications

IF, IHC

Reactivity

Mouse