Cryopyrin antibody

SKU: orb101128

Description

Cryopyrin antibody

Images & Validation

• Tested Applications: IHC-P
• Dilution range: IHC-P: 1:100-1:500

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human Cryopyrin. Please contact us for the exact immunogen sequence. The peptide is available as orb374803.
• Target: Cryopyrin
• Molecular Weight: 118 kDa
• Purity: Polyclonal antibodies are purified by peptide affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 10 mM PBS, 0.02% sodium azide
• Concentration: - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml
• Disclaimer: For research use only

Alternative Names

anti AGTAVPRL antibody, anti C1orf7 antibody, anti Caterpiller protein 1.1 antibody, anti CIAS 1 antibody, anti CIAS1 antibody, anti FCAS antibody, anti FCU antibody, anti MWS antibody, anti NACHT antibody, anti NALP3 antibody, anti NALP 3 antibody, anti NALP-3 antibody, anti NLRP3 antibody, anti PYPAF 1 antibody, anti PYPAF1 antibody, anti PYRIN containing APAF1 like protein 1 antibody

Immunohistochemical staining of rat stomach tissue using Cryopyrin antibody (2.5ug/ml)

IHC-P staining of mouse testis tissue using anti-Cryopyrin (2.5ug/ml)

IHC-P image of rat colon tissue using anti-Cryopyrin (2.5ug/ml)

Immunohistochemical staining of paraffin embedded rat colon tissue using Cryopyrin antibody (2.5ug/ml)

Immunohistochemical staining of mouse lung tissue using Cryopyrin antibody (2.5ug/ml)

Quick Database Links

Gene Symbol

Cryopyrin

UniProt

Q96P20, Q8R4B8

NCBI Gene ID

114548

RefSeq:11, 21, 001073289, 001079821

References

He, Wei et al. Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model J Neuroinflammation, 16, 78 (2019)

PubMed: 30971286

Applications

IF, WB

Reactivity

Mouse

Wilson, C. Brad et al. Valproic acid effects in the hippocampus and prefrontal cortex in an animal model of post-traumatic stress disorder Behav Brain Res, 268, 72-80 (2014)

PubMed: 24675160

Applications

WB

Reactivity

Rat

He, Xue-Mei et al. Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia Oxid Med Cell Longev, 2020, 2963540 (2020)

PubMed: 33294118

Applications

IHC, WB

Reactivity

Rat and Mouse

Wilson, C. Brad et al. Inflammation and oxidative stress are elevated in the brain, blood, and adrenal glands during the progression of post-traumatic stress disorder in a predator exposure animal model PLoS One, 8, e76146 (2013)

PubMed: 24130763

Applications

WB

Reactivity

Rat