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Anti-Hu CD92 Purified
Catalog Number: orb1088505
| Catalog Number | orb1088505 |
|---|---|
| Category | Antibodies |
| Description | CD92 is a 70 kDa protein with ten transmembrane domains, intracellular N and C teminus, and two glycosylated larger extracellular loops. In the C-terminal domain, there is an ITIM-like sequence. This protein seems to be a choline transporter responsible for delivery of choline into the immune cells, to make it accessible for phospholipid synthesis, as well as a regulator of immune cell signaling. It is expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines. It can also be found on mast cells (but not eosinophils), and weakly on peripheral blood lymphocytes, fibroblasts, epithelial cells, and endothelial cells. |
| Clonality | Monoclonal |
| Clone Number | VIM15 |
| Tested applications | FC, WB |
| Reactivity | Human |
| Isotype | Mouse IgG1 |
| Immunogen | MV4-11 acute myeloid leukemia cells |
| Antibody Type | Primary Antibody |
| Concentration | 1 mg/ml |
| Purity | Purified by protein-A affinity chromatography. |
| Conjugation | Unconjugated |
| Target | CD92 |
| Entrez | 23446 |
| UniProt ID | Q8WWI5 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Alternative names | Anti-CTL1 antibody, anti-CHTL1 antibody, anti-SLC4 Read more... |
| Note | For research use only |
| Application notes | Flow cytometry: Recommended dilution: 1-4 µg/ml |
| Expiration Date | 12 months from date of receipt. |
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD92 (VIM15) purified antibody (concentration in sample 0.6 μg/ml, GAM APC).
Separation of monocytes stained anti-human CD92 (VIM15) purified antibody (concentration in sample 0.6 μg/ml, GAM APC, red-filled) from monocytes unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
