Anti-Hu CD367 Purified

• Catalog Number: orb1467379
• Category: Antibodies
• Description: CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose, fucose, and weakly also to N-acetylglucosamine. It is expressed on dendritic cells, macrophages, monocytes, B cells, and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering, it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.
• Clonality: Monoclonal
• Clone Number: 9E8
• Tested applications: ELISA, FC, ICC
• Reactivity: Human, Primate
• Isotype: Mouse IgG1 kappa
• Immunogen: CD367 ectodomain fused with human Fc
• Antibody Type: Primary Antibody
• Concentration: 1 mg/ml
• Purity: Purified by protein-A affinity chromatography.
• Conjugation: Unconjugated
• Target: CD367
• Hazard Information: Non-Toxic
• Entrez: 50856
• UniProt ID: Q9UMR7
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: DCIR, CLEC4A, LLIR
• Note: For research use only
• Application notes: Flow cytometry: Recommended dilution: 1-4 µg/ml
• Expiration Date: 12 months from date of receipt.

Separation of human monocytes (red-filled) from human lymphocytes (black-dashed) in flow cytometry analysis (surface staining) stained using anti-human CD367 (9E8) purified antibody (concentration in sample 0.6 μg/ml, GAM APC).

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD367 (9E8) purified antibody (concentration in sample 0.6 μg/ml, GAM APC).