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Item 1 of 3
Anti-Hu CD303 Purified
Catalog Number: orb1742787
| Catalog Number | orb1742787 |
|---|---|
| Category | Antibodies |
| Description | CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy. |
| Clonality | Monoclonal |
| Clone Number | 15E3 |
| Tested applications | ELISA, FC, ICC, IHC-Fr |
| Reactivity | Human |
| Isotype | Mouse IgG1 kappa |
| Immunogen | CD303 ectodomain fused with human IgG Fc domain |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Target | CD303 |
| Entrez | 170482 |
| UniProt ID | Q8WTT0 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Alternative names | BDCA2, CLEC4C, DLEC, HECL, CLECSF7, CLECSF11, PRO3 Read more... |
| Note | For research use only |
| Application notes | Flow cytometry: Recommended dilution: 1-5 μg/ml. |
| Expiration Date | 12 months from date of receipt. |
Flow cytometry multicolor surface staining of human peripheral blood mononuclear cells stained using CD303 (15E3) purified antibody (concentration in sample 3 μg/ml, GAM FITC) and anti-human CD123 (6H6) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Separation of human CD303 positive CD123 positive plasmacytoid dendritic cells (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD303 (15E3) purified antibody (concentration in sample 3 μg/ml, GAM FITC).
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD303 (15E3) purified antibody (concentration in sample 3 μg/ml, GAM FITC).
