CD209 Antibody

SKU: orb154381

Description

Mouse monoclonal antibody to CD209 which is a member of the chromosome 19 C-type lectin family that includes DC-SIGN, DC-SIGN-related protein, CD23 and LSECtin. It was originally identified in human placenta for its ability to bind the HIV envelope protein gp120 in a CD4-independent manner. CD209 may play a role in T-dendritic cell interactions through binding with members of the ICAM family.

Research Area

Epigenetics, Immunology, Infectious Diseases

Images & Validation

• Tested Applications: FC, ICC, IHC
• Reactivity: Human
• Application Notes:
  Flow cytometry: Recommended dilution: 1-4 μg/ml.

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG2a
• Clone No.: UW60.1
• Immunogen: CD209-His-tagged fusion protein
• Target: CD209
• Purification: Purified by protein-A affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CLEC4L, DC-SIGN1, CDSIGN

Separation of human myeloid cells (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human stimulated (GM-CSF+IL-4) peripheral blood mononuclear cells stained using anti-human CD209 (UW60.1) purified antibody (concentration in sample 0.6 μg/ml, GAM APC).

Flow cytometry surface staining pattern of human stimulated (GM-CSF+IL-4) peripheral blood mononuclear cells stained using anti-human CD209 (UW60.1) purified antibody (concentration in sample 0.6 μg/ml, GAM APC).

Quick Database Links

Gene Symbol

CD209

UniProt

Q9NNX6

NCBI Gene ID

30835