Anti-CSF2Rb / CD131 Reference Antibody (CSL311)

• Catalog Number: orb1806062
• Category: Antibodies
• Description: Anti-CSF2Rb / CD131 Reference Antibody is expressed from CHO. The heavy chain type is huIgG4, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
• Clonality: Monoclonal
• Tested applications: ELISA, FA, FACS, Kinetics
• Reactivity: Human
• Isotype: IgG
• Purity: > 95%
• Conjugation: Unconjugated
• MW: 145.5 kDa
• Target: CSF2Rb / CD131
• Endotoxins: < 1 EU/mg
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 100 mM Pro-Ac 20 mM Arg pH 5.0
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Anti-CSF2Rb / CD131 Reference Antibody (CSL311) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-CSF2Rb / CD131 Reference Antibody (CSL311)is more than 98.34% ;determined by SEC-HPLC.

Immobilized human CSF2RB His at 2 μg/mL can bind Anti-CSF2Rb / CD131 Reference Antibody (CSL311);EC50=0.0122μg/mL.

Human CSF2RB HEK293 cells were stained with Anti-CSF2Rb / CD131 Reference Antibody (CSL311) and negative control protein respectively; washed and then followed by PE and analyzed with FACS; EC114=0.049 μg/mL.

IL-3-mediated proliferation of TF-1 can be completely blocked by antibodies with an IC50 of 0.2109 nM.

GM-CSF-mediated proliferation of TF-1 can be completely blocked by antibodies with an IC50 of 4.105 nM.